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Low Acute Toxicity Eye Preservative Polyquaternium-1/Polidronium Chloride/Pq-1/CAS No. 75345-27-6

Short Description:

Polyquaternium-1 is a very safe preservative, which shows very low acute toxicity in rats.Polyquaternium-1 is slightly toxic orally (LD50> 4.47 ml/l at 40% active in rats). Polyquaternium-1 is not irritating to skin at 40%. The product is not a skin sensitizer and is non-mutagenic.


  • Product Name: Polyquaternium-1  
  • Product Code: YNR-PQ01
  • Synonyms: Polidronium Chloride,PQ-1
  • CAS NO.: 75345-27-6  
  • Molecuar Formula: C22H48Cl3N3O6
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    Low Acute Toxicity Eye Preservative Polyquaternium-1/Polidronium Chloride/Pq-1/CAS No. 75345-27-6 Detail:

    We have now a skilled, performance group to offer excellent support for our consumer. We usually follow the tenet of customer-oriented, details-focused for Low Acute Toxicity Eye Preservative Polyquaternium-1/Polidronium Chloride/Pq-1/CAS No. 75345-27-6, Customer pleasure is our main objective. We welcome you to set up business relation with us. For even further information, make sure you will not wait to contact with us.
    We have now a skilled, performance group to offer excellent support for our consumer. We usually follow the tenet of customer-oriented, details-focused for China Polyquaternium-1, Polyquaternium-1, polyquaternium-1 liquid, Polyquaternium-1 manufacturer, polyquaternium-1 powder, Faced with the vitality of the global wave of economic integration, we’ve been confident with our high-quality goods and sincerely service to all our customers and wish we can cooperate with you to create a brilliant future.
    Polyquaternium-1 is a detergent-type preservative derived from BAK,also named as Polidronium Chloride,PQ-1.Polyquaternium-1 is formulated in the mid of 1980s by Alcon as a preservative for contact lens storage solutions.Nowadays,it is being increasingly used as a presverative in ophthalmic drops for glaucoma, artificial tear solutions and top cosmetic formuations.

    Polyquaternium-1 is a cationic polymer prepared by the controlled polymerization of dimethylamine and bis-dichlorobutene, end capped with tris-b-Hydroxyethylamine.

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    Key Technical Parameters:

    (1) 95~100% Solid:

    Appearance Amber to dark brown solid
    Odor Without Stimulation
    Water solubility Full Soluble
    Free Amine 5.0%
    pH 6.0~9.0
    Chloride <30%
    Internal standard content ≥95%
    Total Number of Aerobic Microbial Count(TAMC)  cfu/g <10³ cfu/g
    Total Yeasts and Molds Count(TYMC) cfu/g <10² cfu/g

    (2) 40% liquid :

    Appearance Light yellow liquid
    Odor Without Stimulation
    Molecular Weight 30,000~40,000
    Solid Content ≥33%
    Chloride ≤10%
    Free Amin ≤2.0%
    pH 6~9
    Water Solubility 100% Soluble
    Total Aerobic Microbial Count(TAMC) <1000cfu/g
    Total Yeasts and Molds Count(TYMC) <100 cfg/g

    Applications:

    Polyquaternium-1is an antimicrobial preservative, with higher antimicrobial effects and lower ocular irritation.used as bactericide in eye drops,soft lenses product and other ophalmic care products formulation.In skin care formulations,it can help to avoid or reduce the allergy and infection possibility.

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    *Preservative

    *Antimicrobial for use in products targeting mucus membrane or other sensitive tissue

    *Antimicrobial for use in dermatological applications and trans-dermal patch pharmaceuticals

    *Antimicrobial for use as surface protection for medical devices

    Toxicity:

    Polyquaternium-1 is a very safe preservative, which shows very low acute toxicity in rats.Polyquaternium-1 is slightly toxic orally (LD50> 4.47 ml/l at 40% active in rats). Polyquaternium-1  is not irritating to skin at 40%. The product is not a skin sensitizer and is non-mutagenic.


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    Low Acute Toxicity Eye Preservative Polyquaternium-1/Polidronium Chloride/Pq-1/CAS No. 75345-27-6 detail pictures

    Low Acute Toxicity Eye Preservative Polyquaternium-1/Polidronium Chloride/Pq-1/CAS No. 75345-27-6 detail pictures

    Low Acute Toxicity Eye Preservative Polyquaternium-1/Polidronium Chloride/Pq-1/CAS No. 75345-27-6 detail pictures

    Low Acute Toxicity Eye Preservative Polyquaternium-1/Polidronium Chloride/Pq-1/CAS No. 75345-27-6 detail pictures

    Low Acute Toxicity Eye Preservative Polyquaternium-1/Polidronium Chloride/Pq-1/CAS No. 75345-27-6 detail pictures

    Low Acute Toxicity Eye Preservative Polyquaternium-1/Polidronium Chloride/Pq-1/CAS No. 75345-27-6 detail pictures

    Low Acute Toxicity Eye Preservative Polyquaternium-1/Polidronium Chloride/Pq-1/CAS No. 75345-27-6 detail pictures


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    Low Acute Toxicity Eye Preservative Polyquaternium-1/Polidronium Chloride/Pq-1/CAS No. 75345-27-6 , The product will supply to all over the world, such as: , , ,

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