Ingredient L- (+) -Ergothioneine CAS 497-30-3

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Ergothioneine(EGT) is an important active substance in human boday.Ergothioneine is obtained by multi fermentation of Hericium Erinaceum & Tricholoma Matsutake.Multi fermentation can increase the yield of L-Ergothioneine,which is a sulfur-containing derivative of the amino acid histidine,a unique stable antioxidant and cytoprotective agent,existing in the human body.Ergothioneine can be transferred inside mitochondria by the transporter OCTN-1 in skin keratinocytes and fibroblasts,thus playing the anti-oxidation and protection functions there.

Product Name: Ergothioneine

Product Code: YNR-EGT

Synonyms: L-Ergothioneine,EGT

INCI Name: Ergothioneine

CAS No.: 497-30-3

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Ergothioneine(EGT) is an important active substance in human boday.Ergothioneine is obtained by multi fermentation of Hericium Erinaceum & Tricholoma Matsutake.Multi fermentation can increase the yield of L-Ergothioneine,which is a sulfur-containing derivative of the amino acid histidine,a unique stable antioxidant and cytoprotective agent,existing in the human body.Ergothioneine can be transferred inside mitochondria by the transporter OCTN-1 in skin keratinocytes and fibroblasts,thus playing the anti-oxidation and protection functions there.

EGT is accumulated into different cellular compartments via its specific transporter OCTN-1,abundantly expressed in mitochondrial DNA is especially vulnerable to stress because unlike nuclear DNA,there are no histones to protect mitochondrial DNA.Reactive oxygen species,like superoxides O₂^- generated in the mitochondria by respiration,are directly scavenged by EGT.EGT presents in the cytoplasm also scavenges a variety of ROS and reactive nitrogen species.EGT absorbs UV radiation and prevents DNA breaks and mutations.Key Technical Parameters

Appearance	White Powder
Assay	99% min.
Loss on Drying	1% max.
Heavy Metals(as Pb)	10 ppm max.
Arsenic	2 ppm max.
Lead	2 ppm max.
Mercury	1 ppm max.
E.Coli	Negative
Total Plate Count	1,000 cfu/g max.
Yeast and Mold	100 cfu/g max.