Hydroxyphenyl Propamidobenzoic Acid
Hydroxyphenyl propamidobenzoic acid(HPA) is an anti-irritant and anti-itch molecule that copies the active ingredient ( Avenanthramides) in the well-known soothing plant oat.This results in the skin feeling comfortable and smooth and can effectively soothe any dryness or flakiness to the skin that frequently occurs during the colder months or for those who suffer with drying skin conditions, such as, eczema and dermatitis. This ingredient is nourishing and stable making it easily added into all manner of cosmetic products.
Hydroxyphenyl propamidobenzoic acid (HPA) is a white crystalline powder with antimicrobial and anti-inflammatory properties. It was first synthesized in 2012 and has shown potential for use in various fields of research and industry. Hydroxyphenyl propamidobenzoic acid(HPA) has been found to possess antimicrobial and anti-inflammatory properties. It has shown activity against various bacterial strains such as Staphylococcus aureus and Escherichia coli.
Hydroxyphenyl Propamidobenzoic Acid CAS NO. 697235-49-7 was widely used in the 19th century to deal with skin problems, mainly by inhibiting histamine signal transduction to achieve anti-inflammatory and antipruritic effects. Hydroxyphenyl Propamidobenzoic Acid CAS NO. 697235-49-7 have the effects of anti allergy, anti-inflammatory, antioxidant, anti irritation, and improving erythema. It can alleviate or improve symptoms such as itching, irritation, and redness in sensitive skin, and are widely used in fields such as cosmetics.
In the field of cosmetics, Hydroxyphenyl Propamidobenzoic Acid CAS NO. 697235-49-7 can alleviate skin redness and itching in private areas, relieve head itching, and are increasingly used in cleansing products, post sun repair products, and skincare products. Hydroxyphenyl Propamidobenzoic Acid CAS NO. 697235-49-7 have multifunctional anti-inflammatory activities, including inhibition of I κ B- α Degradation (NF- κ B’s inhibitory protein), blocking NF-κB The phosphorylation of the subunit p65 protein of B blocks the process of cellular inflammation; Reduce the occurrence of inflammatory immune reactions and the response to skin neurodermatitis.
Key Technical Parameters:
| Appearance | White to off-white crystalline powder |
| Assay | 99%min |
| Melting point | 188℃~200℃ |
| Loss on Drying |
0.5%max. |
| Chloride |
0.05%max. |
| Residue on Ignition |
0.1%max. |
| Total Bacterial | 1,000 cfu/g max. |
| Molds&Yeasts | 100 cfu/g max. |
| E.Coli | Negative/g |
| Staphylococcus Aureus | Negative/g |
| P.Aeruginosa | Negative/g |
Functions:
1. Hydroxyphenyl propamidobenzoic acid (HPA) has the effects of anti-allergy, anti-inflammation, anti-oxidation, anti-stimulation, and improving erythema.
2. Hydroxyphenyl propamidobenzoic acid (HPA) can alleviate or improve the symptoms of itching, irritation, redness and other symptoms of sensitive skin, and is widely used in medicine, cosmetics and other fields.
Applications:
1. In the field of medicine, Hydroxyphenyl propamidobenzoic acid (HPA) can replace glucocorticoids and be used as an anti-inflammatory and antipruritic agent in various skin cream products to treat contact dermatitis, eczema, tinea pedis and other diseases;
2. In the field of cosmetics, Hydroxyphenyl propamidobenzoic acid (HPA) can alleviate skin erythema and itching in private parts, relieve itching, and are more and more widely used in washing products, post-sun repair products, and skin care products.
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