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Factory made hot-sale Pharmaceutical Chemical Alpha Arbutin CAS 84380-01-8

Short Description:

Alpha-Arbutin (4- Hydroxyphenyl-±-D-glucopyranoside) is a pure, water soluble, biosynthetic active ingredient. Alpha-Arbutin blocks epidermal melanin synthesis by inhibiting enzymatic oxidation of Tyrosine and Dopa. Arbutin appears to have fewer side effects than hydroquinone at similar concentrations – presumably due to the more gradual release. It is the more effective, faster and safer approach to promoting skin-brightening and an even skin tone on all skin types. Alpha-Arbutin also minimizes liver spots and meets all the requirements of a modern skin-brightening and skin depigmentation product.


  • Product Name: Alpha-Arbutin
  • INCI Name: Alpha-Arbutin
  • CAS No.: 84380-01-8
  • Molecular Formula: C12H16O7
  • Product Detail

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    Alpha-Arbutin is a biosynthetic glycoside with excellent skin lightening properties for a perfect even skin tone.  It is able to effectively inhibit melanin synthesis by inhibition of tyrosinase, this effect is achievable even at very at low concentrations.

    Alpha Arbutin exhibits impressive tyrosinase inhibition and is nine times more effective than Beta-Arbutin. Very low IC50 values indicates the power of  Alpha-Arbutin. The outstanding efficacy of Alphar-Arbutin is due to its perfect affinity to the active site of tyrosinase.

    Alpha-Arbutin is water soluble and easily incorporated into the water phase of cosmetic formulations. It is stable againsthydrolysis as tested in the pH range from 3.5 – 6.6. Suggested concentration: 0.2% when formulated with an exfoliant or penetration enhancer, otherwise up to 2%.

    arbutin-7

    Key Technical Parameters:

    Appearance White Crystalline Powder
    Assay 99.0% min.
    Melting Point 202~207℃
    Clarity of Water Solution Transparency,colorless,none suspended matters
    pH Value(1% in water) 5.0~7.0
    Specific Optical Rotation 【ɑ】D20=+176~184°
    Arsenic 2ppm max.
    Hydroquinone 10ppm max.
    Heavy Metals 10ppm max.
    Loss on Drying 0.5% max.
    Residue Ignition 0.5% max.
    Pathogen Bacteria:100cfg/g max.Fungus:100 cfu/g max.

    Product Features:

    • INCI name (active): Alpha-Arbutin
    • Scientifically proven effects at low concentrations
    • More effective at 1.0% than Beta-Arbutin in vivo
      – Nine times more effective than Beta-Arbutin in vitro
      – Outstanding tyrosinase inhibition activity in vitro
    • Highly pure biosynthetic active ingredient
    • High performing enzyme related biotechnology
    • Does not contain intentionally added substances regulated/listed as preservative
    • Halal compliant (porcine and alcohol free, not certified)

    Benefits:

    • Ensures an even skin tone after only one month
    • Reduces the degree of skin tanning after UV exposure
    • Helps to minimize the appearance of liver spot

    Arbutin-6

    Package:

    1kg per aluminum foil bag and PE bag lining, 1obags/ carton box or 25bags/fibre drum

    201901051513194934217


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