factory low price China Povidone K30 CAS 9003-39-8 Pharma Grade
factory low price China Povidone K30 CAS 9003-39-8 Pharma Grade Detail:
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Povidone is homopolymer of 1-vinyl-2-pyrrolidone (Polyvinylpyrrolidone),freely soluble in water,in ethanol (96%),in methanol,and other organic solvents,veryslightly soluble in acetone.It’s a hygroscopic polymer ,supplied in white or creamy white powder or flakes,ranging from low to high viscosity & low to high molecular weight,which characterized by K Value,with excellent hygroscopisty,film-forming,adhesive,chemical stability and toxicological safeness characters.
Key Technical Parameters:
|
Product |
Povidone K15 |
Povidone K17 |
Povidone K25 |
Povidone K30 |
Povidone K90 |
| Appearance | White or yellowish-white,hygroscopic powder or flakes | ||||
| Solubility | Freely soluble in water in ethanol(96%)and in methanol,very slightly soluble in acetone | ||||
| Appearance of Solution | Clearly and not more intensely coloured than reference solution B6,BY6 or R6 | ||||
| Identification | A. IR spectrum obtained is consistent with that abtained with Povidone CRS. | ||||
| B.An orange-yellow precipitate is formed | |||||
| C.A pink colour is produced | |||||
| D.A red colour is produced | |||||
| E.The substance dissolves | |||||
| pH(5% in water) | 3.0~5.0 | 3.0~5.0 | 3.0~5.0 | 3.0~5.0 | 4.0~7.0 |
| K Value | 12.75~17.25 | 15.30~18.36 | 22.50~27.00 | 27.00-32.40 | 81.00~97.20 |
| Aldehydes | 500 ppm max. | 500 ppm max. | 500 ppm max. | 500 ppm max. | 500 ppm max. |
| Peroxides | 400 ppm max. | 400 ppm max. | 400 ppm max. | 400 ppm max. | 400 ppm max. |
| Formic Acid | 0.5% max. | 0.5% max. | 0.5% max. | 0.5% max. | 0.5% max. |
| Hydrazine | 1 ppm max. | 1 ppm max. | 1 ppm max. | 1 ppm max. | 1 ppm max. |
| Impurity A | 10 ppm max. | 10 ppm max. | 10 ppm max. | 10 ppm max. | 10 ppm max. |
| Impurity B | 3.0% max. | 3.0% max. | 3.0% max. | 3.0% max. | 3.0% max. |
| Heavy Metals | 10 ppm max. | 10 ppm max. | 10 ppm max. | 10 ppm max. | 10 ppm max. |
| Water | 5.0% max. | 5.0% max. | 5.0% max. | 5.0% max. | 5.0% max. |
| Sulphated Ash | 0.1% max. | 0.1% max. | 0.1% max. | 0.1% max. | 0.1% max. |
| Nitrogen Content | 11.5~12.8% | 11.5~12.8% | 11.5~12.8% | 11.5~12.8% | 11.5~12.8% |
Applications:
Povidone posses excellent binding,film-forming,dispersing and thickening properties.it’s one of the most important excipient in the worldwide for pharmaceutical industry,whatever for human health care products or animal health care products.Which widely used in the pharmaceutical industry as:1)Binder for tables,capsule.It’s suitable for wet and dry granulation and direct compression in tableting,improving the particle compressibility and can be added to powder blends in dry or dissolved by water,alcohol.2)Sugar coatings and films,3)Solubility Improver for poorly soluble drugs,4)Bioavailability Enhancer for drug’s active ingredients,5)Pore-forming for membrane products.
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