Chinese Professional China Cosmetic Grade CAS 84380-01-8 for Whitening Additives Alpha-Arbutin

Short Description:

Alpha-Arbutin (4- Hydroxyphenyl-±-D-glucopyranoside) is a pure, water soluble, biosynthetic active ingredient. Alpha-Arbutin blocks epidermal melanin synthesis by inhibiting enzymatic oxidation of Tyrosine and Dopa. Arbutin appears to have fewer side effects than hydroquinone at similar concentrations – presumably due to the more gradual release. It is the more effective, faster and safer approach to promoting skin-brightening and an even skin tone on all skin types. Alpha-Arbutin also minimizes liver spots and meets all the requirements of a modern skin-brightening and skin depigmentation product.

Product Name: Alpha-Arbutin

INCI Name: Alpha-Arbutin

CAS No.: 84380-01-8

Molecular Formula: C12H16O7

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Alpha Arbutin exhibits impressive tyrosinase inhibition and is nine times more effective than Beta-Arbutin. Very low IC50 values indicates the power of Alpha-Arbutin. The outstanding efficacy of Alphar-Arbutin is due to its perfect affinity to the active site of tyrosinase.

Alpha-Arbutin is water soluble and easily incorporated into the water phase of cosmetic formulations. It is stable againsthydrolysis as tested in the pH range from 3.5 – 6.6. Suggested concentration: 0.2% when formulated with an exfoliant or penetration enhancer, otherwise up to 2%.

Key Technical Parameters:

Appearance	White Crystalline Powder
Assay	99.0% min.
Melting Point	202~207℃
Clarity of Water Solution	Transparency,colorless,none suspended matters
pH Value(1% in water)	5.0~7.0
Specific Optical Rotation	【ɑ】D20=+176~184°
Arsenic	2ppm max.
Hydroquinone	10ppm max.
Heavy Metals	10ppm max.
Loss on Drying	0.5% max.
Residue Ignition	0.5% max.
Pathogen	Bacteria:100cfg/g max.Fungus:100 cfu/g max.

Product Features:

INCI name (active): Alpha-Arbutin
Scientifically proven effects at low concentrations
More effective at 1.0% than Beta-Arbutin in vivo
– Nine times more effective than Beta-Arbutin in vitro
– Outstanding tyrosinase inhibition activity in vitro
Highly pure biosynthetic active ingredient
High performing enzyme related biotechnology
Does not contain intentionally added substances regulated/listed as preservative
Halal compliant (porcine and alcohol free, not certified)