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Best-Selling - Povidone – Y&R

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Best-Selling - Povidone – Y&R Detail:

Povidone is homopolymer of 1-vinyl-2-pyrrolidone (Polyvinylpyrrolidone),freely soluble in water,in ethanol (96%),in methanol,and other organic solvents,veryslightly soluble in acetone.It’s a hygroscopic polymer ,supplied in white or creamy white powder or flakes,ranging from low to high viscosity & low to high molecular weight,which characterized by K Value,with excellent hygroscopisty,film-forming,adhesive,chemical stability and toxicological safeness characters.

Key Technical Parameters:

Product

Povidone K15

Povidone K17

Povidone K25

Povidone K30

Povidone K90

Appearance White or yellowish-white,hygroscopic powder or flakes
Solubility                    Freely soluble in water in ethanol(96%)and in methanol,very slightly soluble in acetone
Appearance of  Solution Clearly and not more intensely coloured than reference solution B6,BY6 or R6
Identification A. IR spectrum obtained is consistent with that abtained with Povidone CRS.
B.An orange-yellow precipitate is formed
C.A pink colour is produced
D.A red colour is produced
E.The substance dissolves
pH(5% in water) 3.0~5.0 3.0~5.0 3.0~5.0 3.0~5.0 4.0~7.0
K Value 12.75~17.25 15.30~18.36 22.50~27.00 27.00-32.40 81.00~97.20
Aldehydes 500 ppm max. 500 ppm max. 500 ppm max. 500 ppm max. 500 ppm max.
Peroxides 400 ppm max. 400 ppm max. 400 ppm max. 400 ppm max. 400 ppm max.
Formic Acid 0.5% max. 0.5% max. 0.5% max. 0.5% max. 0.5% max.
Hydrazine 1 ppm max. 1 ppm max. 1 ppm max. 1 ppm max. 1 ppm max.
Impurity A 10 ppm max. 10 ppm max. 10 ppm max. 10 ppm max. 10 ppm max.
Impurity B 3.0% max. 3.0% max. 3.0% max. 3.0% max. 3.0% max.
Heavy Metals 10 ppm max. 10 ppm max. 10 ppm max. 10 ppm max. 10 ppm max.
Water 5.0% max. 5.0% max. 5.0% max. 5.0% max. 5.0% max.
Sulphated    Ash 0.1% max. 0.1% max. 0.1% max. 0.1% max. 0.1% max.
Nitrogen Content 11.5~12.8% 11.5~12.8% 11.5~12.8% 11.5~12.8% 11.5~12.8%

Applications:

Povidone posses excellent binding,film-forming,dispersing and thickening properties.it’s one of the most important excipient in the worldwide for pharmaceutical industry,whatever for human health care products or animal health care products.Which widely used in the pharmaceutical industry as:1)Binder for tablets,capsules.It’s suitable for wet and dry granulation and direct compression in tableting,improving the particle compressibility and can be added to powder blends in dry or dissolved by water,alcohol.2)Sugar coatings and films,3)Solubility Improver for poorly soluble drugs,4)Bioavailability Enhancer for drug’s active ingredients,5)Pore-forming for membrane products.


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Best-Selling - Povidone – Y&R , The product will supply to all over the world, such as: , , ,

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