Alpha-Arbutin CAS 84380-01-8 for Skin Whitening

Short Description:

Alpha-Arbutin (4- Hydroxyphenyl-±-D-glucopyranoside) is a pure, water soluble, biosynthetic active ingredient. Alpha-Arbutin blocks epidermal melanin synthesis by inhibiting enzymatic oxidation of Tyrosine and Dopa. Arbutin appears to have fewer side effects than hydroquinone at similar concentrations – presumably due to the more gradual release. It is the more effective, faster and safer approach to promoting skin-brightening and an even skin tone on all skin types. Alpha-Arbutin also minimizes liver spots and meets all the requirements of a modern skin-brightening and skin depigmentation product.

Product Name: Alpha-Arbutin

INCI Name: Alpha-Arbutin

CAS No.: 84380-01-8

Molecular Formula: C12H16O7

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Alpha-Arbutin is a biosynthetic glycoside with excellent skin lightening properties for a perfect even skin tone. It is able to effectively inhibit melanin synthesis by inhibition of tyrosinase, this effect is achievable even at very at low concentrations.

Alpha Arbutin exhibits impressive tyrosinase inhibition and is nine times more effective than Beta-Arbutin. Very low IC50 values indicates the power of Alpha-Arbutin. The outstanding efficacy of Alphar-Arbutin is due to its perfect affinity to the active site of tyrosinase.

Alpha-Arbutin is water soluble and easily incorporated into the water phase of cosmetic formulations. It is stable againsthydrolysis as tested in the pH range from 3.5 – 6.6. Suggested concentration: 0.2% when formulated with an exfoliant or penetration enhancer, otherwise up to 2%.

Key Technical Parameters:

Appearance	White Crystalline Powder
Assay	99.0% min.
Melting Point	202~207℃
Clarity of Water Solution	Transparency,colorless,none suspended matters
pH Value(1% in water)	5.0~7.0
Specific Optical Rotation	【ɑ】D20=+176~184°
Arsenic	2ppm max.
Hydroquinone	10ppm max.
Heavy Metals	10ppm max.
Loss on Drying	0.5% max.
Residue Ignition	0.5% max.
Pathogen	Bacteria:100cfg/g max.Fungus:100 cfu/g max.

Product Features:

INCI name (active): Alpha-Arbutin
Scientifically proven effects at low concentrations
More effective at 1.0% than Beta-Arbutin in vivo
– Nine times more effective than Beta-Arbutin in vitro
– Outstanding tyrosinase inhibition activity in vitro
Highly pure biosynthetic active ingredient
High performing enzyme related biotechnology
Does not contain intentionally added substances regulated/listed as preservative
Halal compliant (porcine and alcohol free, not certified)